Interleukin 27 Could Be Useful in the Diagnosis of Tuberculous Pleural Effusions

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Interleukin 27 could be useful in the diagnosis of tuberculous pleural effusions.

BACKGROUND The diagnosis of tuberculous pleural effusion (TBPE) has some limitations. We studied the efficacy of interleukin-27 (IL-27) in the diagnosis of TBPE. METHODS We measured IL-27, adenosine deaminase (ADA), ADA-2, interferon-gamma (IFNγ), and the ADA·IL-27 and ADA-2·IL-27 products in all the pleural effusion fluids. The diagnostic yield of IL-27 was evaluated with receiver operating ...

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Diagnostic value of interleukin-12 p40 in tuberculous pleural effusions.

The diagnosis of tuberculous pleural effusion (TBPE) is frequently problematic. Several markers of TBPE in pleural fluid have been evaluated, with different results. Pleural effusions from 96 patients were classified on the basis of definitive diagnosis as tuberculous (n = 39), neoplastic (n = 42) or parapneumonic (n = 15). Adenosine deaminase (ADA), ADA isoform ADA-2, interferon (IFN)-gamma, C...

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[Tuberculous pleural effusions].

Tuberculous pleural effusion is a common manifestation of the primary form of the disease or consequence of the reactivation of a latent infection due to the M. tuberculosis. Advances in the laboratory methods have contributed to better diagnose and understand the pathophysiology of the effusion secondary to tuberculosis. However, although a predominant lymphocytic pleural effusion is suspiciou...

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Interleukin-16 in tuberculous and malignant pleural effusions.

The aim of this study was to explore the presence of interleukin (IL)-16 in pleural effusions, the correlation between IL-16 levels and cytological parameters, as well as the chemoattractant activity of IL-16 on CD4+ T-lymphocytes. Total nucleated cell and differential counts, and IL-16 concentrations in the pleural effusion from 32 patients with tuberculous pleurisy and 30 patients with lung c...

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Bilateral Tuberculous Pleural Effusions

Mycobacterium tuberculosis remains a pathogen of con¬ siderable clinical and public health importance. Clas¬ sically, tuberculous pleuritis was regarded as a disease ofyoung adults characterized by a unilateral, lymphocytic exudate with a self-limited short-term course. In the last two decades, how¬ ever, there has been increasing recognition that tuberculous pleuritis is occurring in an older ...

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ژورنال

عنوان ژورنال: Respiratory Care

سال: 2013

ISSN: 0020-1324,1943-3654

DOI: 10.4187/respcare.02749